The top choice for treatment of Siphilis is currently Benzylpenicillin, also known as penicillin G. Penicillin G is not given orally due to how unstable it is in hydrochloric acid of the stomach. Penicillin G is also used to treat:
§ Cellulitis
§ Gonorrhea
§ Meningitis
§ Siphilis
§ Pneumonia
Penicillin G is the only therapy with proof of having a positive effect during pregnancy as well.
For those who are not pregnant and have a severe allergy to penicillin may be treated with:
- Tetracycline: (limited data support)
- Doxycycline: (limited data support)
- Ceftriaxone: (optimal dose not yet known)
- Azithromycine: (Reports of treatment failure)
Considering the alternative treatments are not the well known, or do not have much information of success. The CDC recommends desensitization with penicillin followed by penicillin treatment. All women who are pregnant are also recommended to be desensitized and treated with penicillin. After starting the treatment process, one will have to make frequent visits to the doctor for up to 24 months.
If you have any question to whether or not you have siphilis or any other STD, get tested NOW. The sooner you find out the better. If siphilis is left untreated the disease will lead to serious consequences and most likely death.
The beginning process of treatment may be a little rough on the body. A common reaction known as Jarisch-Herxheimer may occur. The reason for this reaction is due to large quantities of toxins being released into the body as bacteria die, due to antibiotic treatment (such as penicillin.) Typically when treatment first occurs, the death of the bacteria and the endotoxins released due to there death, occurs faster than the body can remove them. In this case, one may experience fever, chills, headache, and myalgias. With siphilis, the duration of Jarisch-Herxheimer is normally only a few hours. However, with other diseases is known to last a lot longer, it all depends on the intensity of the inflammation present.
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